Citrus flavonoid naringenin improves aortic reactivity in streptozotocin-diabetic rats
نویسندگان
چکیده
منابع مشابه
Antiatherogenic Properties of Naringenin, a Citrus Flavonoid
An inverse association between flavonoid intake and coronary heart disease (CHD) has been suggested by a number of epidemiological studies (42,44,54,78). As a consequence, there is considerable interest in investigating the antiatherogenic nature of these compounds. Flavonoids are naturally occurring molecules abundant in fruit, vegetables, nuts, seeds, and beverages, such as tea and wine. Over...
متن کاملNitric oxide and endothelium-dependent effect of Tribulus terrestris feeding on aortic reactivity of streptozotocin-diabetic rats
Background and Objective: Cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. In this study, the effect of chronic administration of Tribulus terrestris (TT) feeding was studied on aortic reactivity of streptozotocin (STZ)-diabetic rats and some underlying mechanisms were investigated. Materials and Methods: Male diabetic rats receive...
متن کاملFlavonoid Naringenin Attenuates Oxidative Stress, Apoptosis and Improves Neurotrophic Effects in the Diabetic Rat Retina
Diabetic retinopathy (DR) is one of the leading causes of decreased vision and blindness worldwide. Diabetes-induced oxidative stress is believed to be the key factor that initiates neuronal damage in the diabetic retina leading to DR. Experimental approaches to utilize dietary flavonoids, which possess both antidiabetic and antioxidant activities, might protect the retinal damage in diabetes. ...
متن کاملThe Effect of Flavonoid Naringenin on Contractile Response of Thoracic Aorta Isolated from Diabetic Rats
Background & Aims: Considering increasing incidence of cardiovascular disorders in diabetes mellitus and some evidence on antioxidant and antidiabetic potentials of naringenin, this study was conducted to evaluate the beneficial effects of 6-week administration of naringenin on contractile reactivity of isolated thoracic aorta in diabetic rats. Methods: Male Wistar rats were divided into contro...
متن کاملTungstate treatment improves Leydig cell function in streptozotocin-diabetic rats.
Oral administration of sodium tungstate to adult male streptozotocin-diabetic rats for 3 months normalized serum levels of glucose, insulin, luteinizing hormone, and follicle-stimulating hormone. These effects were accompanied by an increase in reproductive performance, which was related to a strong improvement in Leydig cell function markers, such as the recovery of the number of Leydig cells ...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmacology
سال: 2012
ISSN: 0253-7613
DOI: 10.4103/0253-7613.96350